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目的:探讨脑卒中后抑郁(PSD)的相关因素。方法:采用汉密尔顿抑郁量表对256例脑卒中患者进行现状调查,数据分析用χ2检验、Logistic回归分析。结果:110例(42.9%)脑卒中患者有抑郁表现;χ2检验表明,负性生活事件、抑郁病史、生活依赖、病变位于前部、多并发症与卒中后抑郁症发病有关,P<0.05;Logistic回归分析表明,负性生活事件、抑郁病史、生活依赖、病变位于前部、多并发症成为PSD的危险因素。结论:脑卒中后抑郁的发生是神经生理、社会心理共同作用的结果。
Objective: To explore the related factors of post-stroke depression (PSD). Methods: 256 cases of stroke patients were surveyed by Hamilton depression scale. The data were analyzed byχ2 test and Logistic regression analysis. Results: The depression was found in 110 patients (42.9%) with stroke; the χ2 test showed that the negative life events, the history of depression, life dependence, the lesions were in the anterior part, and the complication was related to the incidence of post - stroke depression (P <0.05) Logistic regression analysis showed that negative life events, history of depression, life dependence, lesions in the anterior and multiple complications became the risk factors of PSD. Conclusion: Post-stroke depression is the result of neurophysiology and social psychology.