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目的探讨运动对单纯性肥胖症儿童的治疗作用。方法采用假期集中训练形式,对32名诊断为肥胖症儿童进行3周的计划运动,于住院后第1天,检测胆固醇(Chol)、甘油三脂(TRG)、低密度脂蛋白(LDL?C)、胰岛素,测量BMI值,第2天作口服葡萄糖耐量试验(OGTT)。于结束运动疗程当天测量BMI;并以同样方式重复检测代谢指标。用SPSS软件处理数据,比较运动前后变化。结果Chol从(4.71±0.79)mmol/L→(3.62±0.69)mmol/L;TRG从(1.09±0.49)mmol/L→(0.85±0.36)mmol/L;LDL?C从(1.43±0.24)mmol/L→(1.07±0.25)mmol/L瘦素从(47.25±16.69)μg/L→(23.71±11.86)μg/L;BMI从(27.38±2.65)→(25.12±2.38)kg/m2。OGTT试验,运动前3例异常并空腹血糖增高,3例单纯OGTT异常(IGT);运动后仅2例OGTT异常(IGT)并空腹血糖升高,最后诊断2型糖尿病。结论适当运动锻炼能使肥胖儿童BMI降低,脂代谢改善,降低肥胖儿童并发心血管病的危险;适当运动还能改善机体血糖利用,纠正糖耐量异常,降低肥胖儿童患2型糖尿病的风险。
Objective To explore the therapeutic effect of exercise on children with simple obesity. Methods A total of 32 children with obesity were enrolled in this study. Three weeks of planned exercise were performed on the first day after hospitalization. Cholesterol, triglyceride (TRG), low density lipoprotein (LDL? C ), Insulin, BMI measurement, and oral glucose tolerance test (OGTT) on the second day. BMI was measured on the day of end of exercise regimen; and metabolic indices were repeatedly tested in the same manner. Data was processed using SPSS software to compare changes before and after exercise. Results Chol from (4.71 ± 0.79) mmol / L → (3.62 ± 0.69) mmol / L, (1.09 ± 0.49) mmol / L and (47.2 ± 16.69) μg / L → (23.71 ± 11.86) μg / L respectively; BMI was (27.38 ± 2.65) → (25.12 ± 2.38) kg / m2. In the OGTT test, 3 cases were abnormal before exercise and the fasting blood glucose was increased, 3 cases had simple OGTT abnormalities (IGT); only 2 cases had abnormal OGTT (IGT) after exercise and the fasting blood glucose increased. Finally, type 2 diabetes mellitus was diagnosed. Conclusions Proper exercise can reduce BMI, improve lipid metabolism and reduce the risk of cardiovascular disease in obese children. Appropriate exercise can improve blood glucose utilization, correct impaired glucose tolerance and reduce the risk of type 2 diabetes in obese children.