该文采用先进的固体核磁共振技术研究了壳聚糖-聚3-丙烯酰胺基苯硼酸纳米粒子非均匀结构和高分子间的相容性.13C CPMAS实验表征了壳聚糖与苯硼酸结合后的构象变化,2D 13C-1H HETCOR实验进一步证明了壳聚糖在界面处通过硼酸配位作用与苯硼酸链紧密相连.2D 1H-1H自旋交换和扩散实验阐明了壳聚糖和聚苯硼酸的界面混合性,相分离尺度大约为15-20 nm. In this paper, advanced solid-state nuclear magnetic resonance technique was used to study the heterogeneous structure of chitosan-poly (3-acrylamidophenyl) borate nanoparticles and the compatibility between macromolecules.C13M CPMAS experiments showed that chitosan and phenylboronic acid The 2D13C-1H HETCOR experiment further proved that the chitosan was bound to the phenylboronic acid chain through the coordination of boronic acid at the interface.2D 1H-1H spin exchange and diffusion experiments demonstrated that chitosan and polyphenylboronic acid The interfacial mixing, the phase separation scale is about 15-20 nm.