本文记述了 TSH 持续升高的两例女病人TSH 分泌动态。一例为4岁零7个月,另一例为1岁零8个月,尽管血清 T_4浓度正常,各为7.3μg/dl 和7.4μg/dl,但 TSH 浓度非常高,分别为200μU/ml、270μU/ml。两例均有明显的甲状腺组织功能缺如,而且初始的 T_4浓度在可测界限以下。虽然病例1在1岁半时 TSH 曾下降到正常,但随后 TSH 又明显地升高。病例2的 TSH 值一直>40μU/ml。两位病人都有甲状腺毒血症期,在此期间 This article describes TSH secretion in two consecutive women with elevated TSH. One case was 4 years and 7 months and the other was 1 year and 8 months. The TSH concentrations were very high, at 200 uU / ml and 270 uU, respectively, although the serum concentrations of T 4 were normal at 7.3 μg / dl and 7.4 μg / dL, respectively / ml. In both cases, there was a clear absence of thyroid tissue function, and the initial T_4 concentration was below the measurable limit. Although case 1 decreased to normal after 1 year and a half TSH, but TSH then significantly increased. Case 2 TSH value has been> 40μU / ml. Both patients had thyrotoxicosis during this period