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目的评价经纤维支气管镜局部激光联合注药治疗耐多药支气管结核的疗效。方法经纤支镜局部激光联合注药治疗18例(治疗组)耐多药支气管结核,并与同期经雾化治疗的21例(对照组)病人作对照进行病情及疗效的观察。结果治疗组全部病人痰菌阴转,病灶明显吸收好转,除1例病人外所有病人的支气管结核病灶吸收好转;而对照组18例病人痰菌阴转,16例病人痰结核菌培养阴转,支气管结核病灶吸收好转15例,两组疗效差别明显。结论经纤维支气管镜局部激光联合注药治疗耐多药支气管结核,疗效可靠,操作相对简单,安全,是一种对耐多药支气管结核治疗的有效方法。
Objective To evaluate the efficacy of local laser combined with bronchoscopy in the treatment of multidrug-resistant bronchial tuberculosis. Methods 18 cases (treatment group) of multidrug-resistant bronchial tuberculosis were treated with local laser combined with bronchofiberscopy and the control group was treated with 21 cases (control group) of the same period. The disease and curative effect were observed. Results In all patients in the treatment group, sputum negative conversion was found and the lesions were obviously absorbed. The bronchial tuberculosis lesions of all patients except one patient were improved. In the control group, 18 patients had sputum negative conversion and 16 patients had sputum TB culture, Bronchial tuberculosis lesions improved in 15 cases, the two groups showed significant differences in the efficacy. Conclusions The combination of local bronchofibroscopy and laser injection of multidrug-resistant bronchial tuberculosis is a reliable and safe method to treat multidrug-resistant bronchial tuberculosis. It is an effective method to treat multidrug-resistant bronchial tuberculosis.