氮杂环化合物是杂环化合物的重要组成部分.作为许多具有生理活性的生物碱、医药化合物的基本骨架,含氮的杂环化合物的合成有巨大的应用价值.近年来,纳米金属氧化物作为一种绿色非均相的催化剂在氮杂环的构成方面有越来越广泛的应用,综述了近五年来纳米金属氧化物在催化含氮杂环化合物合成研究的新进展. Nitrogen heterocyclic compounds are an important part of heterocyclic compounds.As the basic structure of many physiologically active alkaloids, pharmaceutical compounds, the synthesis of nitrogen-containing heterocyclic compounds has great application value.In recent years, nano-metal oxides as the A green heterogeneous catalyst has more and more applications in the formation of nitrogen heterocycles. The recent progress in the synthesis of nitrogen-containing heterocyclic compounds catalyzed by nano-metal oxides in recent five years is reviewed.