Accumulating evidence has revealed that brain iron concentrations increase with aging, and the choroid plexus may be at the basis of iron-mediated toxicity
The homeostasis of magnesium (Mg2+), an abundant divalent cation indispensable for many biological processes including mitochondrial functions, is underexpl
Copper is vital to cell function.The influx of reduced copper ions is controlled by homologous transmembrane solute carrier transporter CTR1 (encoded by SLC
Hepcidin is a peptide hormone that is synthesized mainly in the liver.Hepcidin negatively regulates serum iron by controlling iron absorption from diets and
The intracellular iron transfer process is not well understood, and the identity of the iron transporter responsible for iron delivery to the secretory comp
Mammalian iron metabolism is delicately regulated by many modulators.Among them, hepcidin is the key hormone that negatively modulate iorn hemeostasis.Hepci