耳带状疱疹由活化的水痘带状疱疹病毒(VZV)引起。过去对该病中耳粘膜的病理组织学研究甚少。作者之两例耳带状疱疹,保守治疗面瘫无改善。经乳突进路行面神经减压术。除水平段神经及其鞘膜充血水肿外,另发现粘膜在邻近面神经走行处严重充血水肿,一例在水平段另一例在锥隆起。取其粘膜切片,以抗VZV鼠单克隆抗体(抗糖蛋白和抗核壳体蛋白)用于免疫荧光切片上,制成标本,分别在光镜和荧光显微镜下观察。病理组织学所见:病变粘膜间隙有炎症浸润,主要是淋巴细胞和散在的浆细胞。免疫荧光所见:第一例标本的椭圆形细胞的细胞浆和细胞核中,以及第二例标本的圆形细胞的细胞 Herpes zoster is caused by the activated varicella-zoster virus (VZV). In the past the pathology of the middle ear mucosa histopathology little. The authors of two cases of herpes zoster, conservative treatment of facial paralysis no improvement. The mastoid process of facial nerve decompression. In addition to the horizontal section of the nerve and its sheath congestion and edema, another found in the vicinity of the facial nerve mucosa severe congestion and edema, another case in the horizontal section of the cone uplift. The mucosal sections were taken and anti-VZV murine monoclonal antibodies (anti-glycoprotein and anti-nucleocapsid protein) were used on immunofluorescence sections to make specimens which were observed under light microscope and fluorescence microscope respectively. Histopathological findings: Inflammatory lesions in the mucosal space, mainly lymphocytes and scattered plasma cells. Immunofluorescence findings: The first specimen of oval cells in the cytoplasm and nucleus, as well as the second specimen of round cells