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目的:探讨同型半胱氨酸(Hcy)与重症肝炎的关系。方法:测定35例重症肝炎患者血清Hcy水平,同时检测血清TBIL、ALT、AST、m-AST、CHE、GLU、CHO等生化指标的活性与含量,观察Hcy的变化及与各生化指标的相关性。结果:重症肝炎患者血清Hcy明显升高与各生化指标之间有相关性。结论:高Hcy血症可能是重症肝炎的一个危险因素,且与重症肝炎互为因果关系。
Objective: To investigate the relationship between homocysteine (Hcy) and severe hepatitis. Methods: Serum levels of Hcy were measured in 35 patients with severe hepatitis and the activities and contents of serum biochemical indexes such as TBIL, ALT, AST, m-AST, CHE, GLU and CHO were measured. The changes of Hcy and its correlation with biochemical indexes . Results: Serum Hcy was significantly increased in patients with severe hepatitis and all biochemical indexes were correlated. Conclusions: Hyperhomocysteinemia may be a risk factor for severe hepatitis and causal relationship with severe hepatitis.