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目的:探讨口腔癌术后患者甲状腺功能低下的高危因素。方法:回顾性分析我院从2012年7月~2017年5月收治的156例口腔癌患者的临床特征与术后甲状腺功能低下的相关性。结果:156例患者手术前均无甲状腺功能降低,术后有35例患者有甲状腺低下,比例为22.44%。在102例接受放疗的患者中,甲低患者的比例为28.43%,而未接受放疗的54例患者发生甲状腺低下的比例为11.11%,其差异具有统计学意义(P=0.014)。结论:口腔癌术后放疗是导致甲状腺功能低下的高危因素。
Objective: To investigate the risk factors of hypothyroidism in postoperative patients with oral cancer. Methods: A retrospective analysis of our hospital from July 2012 to May 2017 in 156 cases of oral cancer patients with clinical features and postoperative hypothyroidism correlation. Results: None of the 156 patients had hypothyroidism before surgery. Thirty-five patients had hypothyroidism after operation, accounting for 22.44%. Among the 102 patients receiving radiotherapy, the proportion of patients with hypothyroidism was 28.43%, while the percentage of patients with hypothyroidism who were not receiving radiotherapy was 11.11%. The difference was statistically significant (P = 0.014). Conclusion: Postoperative radiotherapy of oral cancer is a risk factor for hypothyroidism.