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目的观察疏血通注射液配合拜阿司匹林治疗下肢动脉疾病(PAD)的临床疗效。方法将186例PAD患者随机分为2组,治疗组92例予疏血通注射液配合拜阿司匹林治疗,对照组94例单用拜阿司匹林治疗,2组疗程均为4周。观察2组踝臂指数(ABI)、脉搏波传导速度(PWV)变化和临床疗效。结果治疗组治疗后ABI较本组治疗前、对照组治疗后均增加(P<0.05,P<0.01),PWV均降低(P<0.05,P<0.01)。2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论疏血通注射液能有效增加ABI,降低PWV,改善PAD患者临床症状。
Objective To observe the clinical efficacy of Shuxuetong injection combined with aspirin in the treatment of lower extremity arterial disease (PAD). Methods One hundred and sixty-six patients with PAD were randomly divided into two groups. 92 cases in the treatment group were treated with Shuxuetong injection plus aspirin, while 94 cases in the control group were treated with aspirin alone. The two courses of treatment were 4 weeks. The ankle-brachial index (ABI), pulse wave velocity (PWV) and clinical efficacy of the two groups were observed. Results After treatment, ABI in treatment group was significantly higher than that in control group before and after treatment (P <0.05, P <0.01), PWV was decreased (P <0.05, P <0.01). The total effective rate in the two groups was statistically significant difference (P <0.05), the treatment group than the control group. Conclusion Shuxuetong injection can effectively increase ABI, reduce PWV, improve the clinical symptoms of PAD.