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本文分析了38例大厂矿井下矿工、40例井上工作人员和27例非矿区正常人的外周血淋巴细胞SCE频率、染色体畸变率和微核率差异情况,发现井下矿工的SCE频率和染色体畸变率显著高于井上工作人员及非矿区正常人,微核率的差异无显著意义(P>0.05)。结合矿区肺癌流行病学调查结果对比分析,认为井下矿工长期接触的生产性粉尘中可能存在一些致癌物质,导致机体细胞遗传物质受到一定程度损伤。
In this paper, we analyzed the difference of SCE frequency, chromosome aberration rate and micronucleus rate of 38 Dachang miners, 40 uphole workers and 27 non-mining normals, and found that the downhole miners’ SCE frequency and chromosome aberration rate Significantly higher than the well workers and non-mining normal, micronucleus rate difference was not significant (P> 0.05). According to the epidemiological survey results of lung cancer in the mining area, it is concluded that there may be some carcinogenic substances in the productive dust that the underground miners come into contact with for a long time, resulting in a certain degree of damage to the genetic material of the body cells.