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1 引言1.1 概念 Wegener肉芽肿 (Wegener’sgranulomatosis ,WG)概念最早由Godman和Churg提出[1 ] ,是病理学概念 ,即为一种暴发性系统性疾病 ,累积多脏器系统 ,是以呼吸道坏死性肉芽肿、弥漫性血管炎和肾小球肾炎三联症为特征 (表1)。临床上分 2型 :(1)局限型或初发性WG ,
1 Introduction 1.1 Concept The concept of Wegener’s granulomatosis (WG) was first proposed by Godman and Churg [1]. It is a concept of pathology that is a kind of fulminant systemic disease. It accumulates multiple organ systems and is characterized by respiratory necrosis Granuloma, diffuse vasculitis and glomerulonephritis triad symptoms (Table 1). Clinically divided into 2 types: (1) localized or primary WG,