目的评价角膜塑形术（ｏｒｔｈｏｋｅｒａｔｏｌｏｇｙ，ＯｒｔｈｏＫ）治疗近视眼的效果。方法采用角膜塑形术治疗８５例（１４０眼）近视眼患者（１７５～７２５Ｄ）。分为３组：Ⅰ组为１７５～３００Ｄ，Ⅱ组为３２５～６００Ｄ，Ⅲ组为６２５～７２５Ｄ。随访３个月。结果Ⅰ组治疗后３个月平均残余屈光度为００４±００９Ｄ，屈光度在±０５０Ｄ以内者为１００％；裸眼视力达１０为１００％。Ⅱ组平均残余屈光度为０３４±０４２Ｄ，屈光度在±０５０和±１００Ｄ以内者分别为８０００％和９４１２％；裸眼视力达０５和１０者分别为９８８２％和７１７６％。Ⅲ组平均残余屈光度为１８４±１０８Ｄ，屈光度在±０５０Ｄ和±１００Ｄ以内者分别为６２５％和３７５０％；裸眼视力达０５和１０者分别为８７５％和６２５％。结论角膜塑形术是治疗１７５～７２５Ｄ近视眼的安全有效方法，无明显影响视力的并发症。 Objective To evaluate the efficacy of orthokeratology (Ortho-K) in the treatment of myopia. Methods 85 cases (140 eyes) of myopia were treated by orthokeratology (175 ~ 725D). Divided into three groups: Ⅰ group  175 ~  300D, Ⅱ group  3  25 ~  6  00D, Ⅲ group  6  25 ~  7  25D. Follow up for 3 months. Results The average remnants of refraction in group Ⅰ after 3 months of treatment were 004 ± 009D, those with refraction within ± 050D were 100%, and the uncorrected visual acuity of 1  0 was 100%. The average remnant diopter in group Ⅱ was 034 ± 042D, and those in ± 050 and ± 100D were 8000% and 9412% respectively. The visual acuity of naked eyes reached 05 and 10 Were 9882% and 7176% respectively. The average remnant diopter in group Ⅲ was 184 ± 108D, and those in ± 050D and ± 100D were 625% and 3750% respectively. The uncorrected visual acuities were 05 and 10 They were 875% and 625% respectively. Conclusion Orthokeratology is a safe and effective method for the treatment of 175 ~ 725 D myopia without any significant effect on visual acuity.