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本文通过经尿道切除综合征(TURS)的实验研究发现:①冲洗液吸收完时,血钠下降最为明显,而它的恢复与血浆甘露醇的消除在时相上并不一致。低钠的影响大且持续的时间长。②冲洗液吸收后,血钾逐渐升高。高钾血症是实验动物死亡的主要原因之一。③等渗的甘露醇冲洗液吸收,血浆渗透压不发生改变。④死亡兔肺重量明显增加,呈肺水肿表现。无脑水肿存在。④根据动物实验推算,经尿道前列腺切除的患者,术中短时间內吸收38ml/kg以上的冲洗液,有发生TURS的可能。上述结果对TURS病理生理改变的认识及其防治提供了实验依据。
In this paper, transurethral resection syndrome (TURS) experimental study found that: ① flushing fluid absorption is completed, the most obvious decline in serum sodium, and its recovery and plasma mannitol in the phase of time is not consistent. The effect of low sodium is large and lasts long. ② After the rinse fluid absorption, serum potassium gradually increased. Hyperkalemia is one of the major causes of death in experimental animals. ③ isotonic mannitol fluid absorption, plasma osmolality does not change. ④ dead rabbit lung weight increased significantly, showed pulmonary edema performance. No brain edema exists. ④ According to animal experiments, transurethral resection of the prostatectomy patients, intraoperative absorption of more than 38ml / kg rinse, there TURS possible. These results provide an experimental basis for the understanding of TURS pathophysiological changes and their prevention and treatment.