论文部分内容阅读
将水合氯醛用丙二醇溶解，灌装于空心栓壳中制成中空栓，既克服了其口服给药的刺激性，也改善了灌肠给药的不便。并对水合氯醛中空栓、口服液剂及灌肠给药进行了临床疗效比较。结果表明，灌肠剂与中空栓的临床疗效无显著差异（ｐ＞０．０５），两者均比口服液剂起效快。
Dissolving chloral hydrate with propylene glycol and filling hollow plug in a hollow shell can not only overcome the irritation of oral administration but also improve the inconvenience of enema administration. The clinical efficacy of chloral hydrate suppository, oral solution and enema was compared. The results showed that enema and hollow suppositories no significant difference in clinical efficacy (p> 0.05), both faster than the oral solution agent onset.