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目的探讨耐多药肺结核运用卷曲霉素与莫西沙星联合治疗的临床疗效.方法将2012年4月至2014年6月我院治疗的82例耐多药肺结核患者随机分为观察组与对照组.分别给予莫西沙星联合卷曲霉素.左氧氟沙星联合阿米卡星进行抗结核治疗.比较两组疗效.结果开始治疗3个月.两组痰菌阴转情况比较差异无统计学意义.治疗6个月开始.两组痰菌阴转情况比较.差异具有统计学意义(P(0.05).结论卷曲霉素联合莫西沙星能有效治疗耐药肺结核.并提高痰菌转阴率.值得推广使用.
Objective To investigate the clinical efficacy of multidrug-resistant pulmonary tuberculosis combined therapy with capreomycin and moxifloxacin.Methods 82 cases of MDR-TB patients treated in our hospital from April 2012 to June 2014 were randomly divided into observation group and control group Were given moxifloxacin combined with capreomycin.Levofloxacin combined with amikacin for anti-TB treatment.Comparison of the two groups of curative effect.Results began to treat for 3 months.The two groups of sputum bacteria negative conversion was no significant difference in treatment 6 (P (0.05)) .Conclusion The combination of capicamycin and moxifloxacin can effectively treat drug-resistant pulmonary tuberculosis and improve the rate of sputum negative conversion, which is worth to promote .