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以前的研究工作曾提出,正常人在接受分子量为65,000到80,000的右旋醣酐1立升或更多后,会引起出血时间延长。这个观察是不能用通常发生的血小板计数稍微减少来解释。血小板吸附于右旋醣酐,可使血浆电泳活动性有改变。右旋醣酐对止血功能产生坏的影响,可能是由于它对血小板功能有抑制作用而起,文献上曾报告过有不同类型的右旋醣酐引起血小板的异常现象,不同分子量的右旋醣酐在试管和活体中妨碍了血小板第三因子的获得。然而,血小板凝血活性的缺陷不好解释出血时间的延
Previous research has suggested that normal individuals who receive 1 liter or more of dextran with a molecular weight of 65,000 to 80,000 may cause prolonged bleeding. This observation can not be explained by the slight decrease in platelet count that usually occurs. Platelets adsorbed on dextran, plasma electrophoresis activity can change. Dextran on hemostasis have a bad effect, probably because it has an inhibitory effect on platelet function, the literature has reported that different types of dextran caused platelet abnormalities, different molecular weight of dextrose Anhydride impedes the attainment of platelet third factor in vitro and in vivo. However, poor platelet coagulation activity is not good to explain the extension of bleeding time