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降压宁(terazosin)系突触后α_1-受体阻滞剂,药代动力学与哌唑嗪相似。但降压持续时间较长,每日口服1次即可。作者随机选择28例高血压病患者(Ⅰ期7例,Ⅱ期21例)用降压宁治疗,以探索国人最合适剂量。用法:第1周每晚睡前服1毫克,剂量每周逐渐增加自2毫克/天,4毫克/天、6毫克/天、10毫克/天直至出现满意疗效,即收缩压/舒张压下降
Terazosin is a post-synaptic alpha 1 -receptor blocker with pharmacokinetics similar to prazosin. However, longer duration of antihypertensive, daily oral administration can be. The authors randomly selected 28 patients with hypertension (7 cases of stage Ⅰ, 21 cases of stage Ⅱ) with antihypertensive treatment in order to explore the most appropriate dose of Chinese. Usage: Week 1 before bedtime every night to take 1 mg, the dose gradually increased from 2 mg / day, 4 mg / day, 6 mg / day, 10 mg / day until the desired effect, ie, systolic / diastolic blood pressure drop