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目的通过对常用中药所含化学物质进行毒理药理研究,概述中药十八反的理论基础。方法急性毒性实验、组织病理学、生物化学等。结果十八反药物相互影响巨大,妨碍疗效,并产生毒性。结论中药成分复杂、临床药剂科工作者需研究成分间相互作用,为中药配伍禁忌提供科学理论依据。
Objective To study the toxicological pharmacology of commonly used traditional Chinese medicines and summarize the theoretical basis of traditional Chinese medicine. Methods Acute toxicity test, histopathology, biochemistry, etc. Results Eighteen anti-drug interactions are huge, hindering efficacy, and producing toxicity. Conclusion The composition of Chinese medicine is complex, and clinical pharmacy workers need to study the interactions between ingredients and provide scientific theoretical basis for the incompatibility of traditional Chinese medicine.