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目的 了解晚期前列腺癌综合治疗的方法及效果。方法 回顾性分析 1990年 1月～ 2 0 0 1年 12月收治的 62例晚期前列腺癌病人 ,采用以内分泌治疗为主的综合治疗措施。结果 随访 6～ 60个月 ,平均 2 4.5月。接受内分泌治疗后病人下尿路梗阻症状均有不同程度缓解 ,前列腺缩小 ,PSA下降。TURP、输尿管皮肤造瘘、局部放疗或同位素内放射治疗等可有效解除尿路梗阻 ,保护肾功能 ,减轻转移性骨痛。结论 对晚期前列腺癌病人应采取积极的综合治疗措施。睾丸切除或口服己烯雌酚 +抗凝剂是经济有效的内分泌治疗方法
Objective To understand the method and effect of comprehensive treatment of advanced prostate cancer. Methods A retrospective analysis of 62 patients with advanced prostate cancer who were admitted between January 1990 and December 2001 was conducted with comprehensive treatment based on endocrine therapy. The results were followed up for 6 to 60 months, an average of 24.5 months. After receiving endocrine therapy, patients with lower urinary tract obstruction symptoms have varying degrees of relief, prostate shrinkage, PSA decreased. TURP, ureteric skin ostomy, local radiotherapy or isotope radiation therapy can effectively relieve urinary tract obstruction, protect renal function and reduce metastatic bone pain. Conclusions Patients with advanced prostate cancer should take active and comprehensive treatment. Resection or oral diethylstilbestrol + anticoagulant is a cost-effective method of endocrine therapy