最早关于糖尿病遗传特性的记载可追溯到公元前1,000～500年,当时是依据家族聚集现象推测的。对双胎的研究确认了糖尿病的遗传性,就糖尿病或糖耐量异常而言,单卵双胎的一致率为45～96%;而双卵双胎的一致率仅3～37%。这种遗传缺陷的本质、传递方式、 The earliest records on the genetic characteristics of diabetes date back to 1, 000 to 500 BC, when speculation was based on familial aggregation. Studies of twins have confirmed the hereditary nature of diabetes. In the case of diabetes or impaired glucose tolerance, the concordance rates of monozygotic twins ranged from 45 to 96%. The identical rate of twins was only 3 to 37%. The nature of this genetic defect, delivery method,