论文部分内容阅读
Background/Aims In industrialized countries hepatitis E virus(HEV) infection is rare and its diagnosis is difficult because the utility of available tests is not well established. Methods We studied the presence of acute HEV infection markers in a cluster of 11 cases of acute hepatitis with IgG anti-HEV antibodies.Results Three cases were confirmed as acute hepatitis E and 8 as presumptive hepatitis E, two as a past HEV infection and one could not be determined. Three different HEV strains were identified in serum from 3 pa tients. Two strains belonged to genotype 3, the predominant genotype found in local urban sewage and the other strain belonged to genotype 1 and was considered an imported strain. Conclusions Our findings demonstrate the presence of some autochthonous, sporadic acute hepatitis E cases as well as an imported case in our area and the transitory nature of virological and serological markers for HEV.
Background / Aims In industrialized countries hepatitis E virus (HEV) infection is rare and its diagnosis is difficult because the utility of available tests is not well established. The utility of available vaccines in a cluster of 11 cases of acute hepatitis with IgG anti-HEV antibodies. Results Three cases were confirmed as acute hepatitis E and 8 as presumptive hepatitis E, two as a past HEV infection and one could not be determined. Three different HEV strains were identified in serum from 3 pa tients. Two The belonged to genotype 3, the predominant genotype found in local urban sewage and the other strains belonged to genotype 1 and was considered an imported strain. Conclusions Our findings demonstrated the presence of some autochthonous, sporadic acute hepatitis E cases as well as an imported case. in our area and the transitory nature of virological and serological markers for HEV.