不明原因的嗜酸粒细胞(EO)增多,伴多脏器浸润的 EO 增多综合征(HES)国内外报道不多,尤以心脏损害为主要表现的 EO 增多性心脏病更为少见。作者遇见1例,报告如下。患者,男,60岁。因咳嗽、咯白痰1年,劳力性心慌、气短1月,于1986年9日入院。体检:高枕卧位,两肺呼吸音粗。心界扩大,心音低,心率120次/分,心尖部Ⅱ级收缩期吹风样杂音及 S_3。肝肋下3cm,脾肋下2cm,双下肢轻度凹陷性水肿。末梢血片:Hb66g/L,WBC14×10~3/L,EO 占80％,部分呈脱颗粒状(图1)。骨髓片:骨髓增生活跃,粒系占有核细胞67％,形态同血片(图2)。痰涂片可见 EO 及夏科氏结晶,X 线胸片显示心包 Eosinophils (EO) of unknown cause increased, EO increased syndrome with multiple organ infiltration (HES) reported little at home and abroad, especially heart damage as the main manifestation of EO more rare heart disease. The authors met in 1 case, the report is as follows. Patient, male, 60 years old. Due to cough, slightly Phlegm 1 year, exertional palpitation, shortness of breath in January, was admitted to hospital on January 9, 1986. Physical examination: high pillow position, both lungs sound rough tone. Expand the heart, low heart sound, heart rate 120 beats / min, apical Ⅱ grade systolic hair-like noise and S_3. Liver ribs 3cm, Spleen ribs 2cm, lower limbs slightly depressed edema. Peripheral blood films: Hb66g / L, WBC14 × 10 ~ 3 / L, EO accounted for 80%, some were degranulation (Figure 1). Marrow slices: active bone marrow proliferation, accounting for 67% of the granulocytes, morphology and blood film (Figure 2). Sputum smear visible EO and Xia Keshi crystallization, X-ray showed pericardium