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目的 :探讨ICU院内真菌感染的特点及危险因素。方法 :对 1998年 1月～ 1999年 12月ICU收治超过 48h的 32 0例患者中发生院内真菌感染的 41例进行调查分析。结果 :ICU院内真菌感染平均第 9 2 6±3 5 4天出现 ,感染率 12 81% ,死之率 5 1 2 1% ,以白色念珠菌感染为主 ,主要感染部位在肺部。结论 :ICU患者年龄、基础疾病、侵袭性操作及抗生素的不合理应用是真菌感染的危险因素。对氟康唑不敏感的非白色念珠菌的治疗应成为今后探讨的重点
Objective: To investigate the characteristics and risk factors of fungal infection in hospital ICU. Methods: 41 cases of nosocomial fungal infections among 32 0 patients admitted to ICU from January 1998 to December 1999 for more than 48 hours were investigated. Results: The average number of fungal infections in hospital was 92.6 ± 3.54 days. The infection rate was 12.81% and the mortality rate was 51.21%. Candida albicans was the main infection and the main infection site was in the lungs. CONCLUSIONS: Age, underlying disease, invasive procedures, and irrational use of antibiotics in ICU patients are risk factors for fungal infections. Treatment of non-Candida albicans that is not susceptible to fluconazole should be the focus of future discussions