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以132-氧代焦脱镁叶绿酸-a甲酯为起始原料,碱性条件下的空气氧化和重排反应定量地将其转化成红紫素-18甲酯;在三氟化硼催化下,与苯乙酮的羟醛缩合反应分别给出131-苯甲酰亚甲基取代的二氢卟吩酮和绿卟啉酮;E-环二酮与丙二腈的Knoevenagel反应、与氨基硫脲的缩合反应和与重氮甲烷的重排反应以及与苄基氯化镁的Grignard反应生成一系列具有长波吸收的叶绿素类二氢卟吩衍生物.首次报道的具有叶绿素基本碳架的二氢卟吩衍生物的化学结构均经UV,IR,1H NMR及元素分析得以证实.
Oxidation of pyropheophorbide-a methyl ester as a starting material, under alkaline conditions of air oxidation and rearrangement reaction quantitatively converted to purpurin-18 methyl ester; boron trifluoride Catalyzed aldol reaction with acetophenone gave 131-benzoylaminophenol and chloroporphyrinone, respectively; Knoevenagel reaction of E-diketone with malononitrile, and The thiosemicarbazone condensation reaction and the rearrangement reaction with diazomethane and the Grignard reaction with benzylmagnesium chloride generated a series of chlorophyll chlorin derivatives with long wave absorption.The first reported dihydro The chemical structures of porphine derivatives were confirmed by UV, IR, 1H NMR and elemental analysis.