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环喹啉(Cycloquin)与氯化喹啉同属4-氨基喹啉类抗瘧药。小白鼠口服LD_(50)为369±51毫克/公斤,稍高于氯化喹啉的461±58毫克。使用时直接以游离硷軋制片剂,即每片只含基质0.075克。作者等对上海地区間日瘧健康儿童带虫者及现症病人口服該药进行了疗效观察,前者为6～14岁学童,服药2片即0.15克;后者为門診患者,多为成年人,服药8片,即0.6克。儿童間日瘧带虫34例,服药后第三天血片复查已
Cycloquin and quinoline chloride belong to 4-amino-quinoline antimalarial. Mice white oral LD_ (50) of 369 ± 51 mg / kg, slightly higher than 461 ± 58 mg of quinoline chloride. When used directly free base rolling tablets, that is, each containing only substrate 0.075 grams. The author of the Shanghai area of vivax malaria healthy children and those who live with oral administration of the drug efficacy of the observation, the former for children aged 6 to 14, taking 2 or 0.15 grams; the latter out-patient patients, mostly adults , Taking 8 tablets, that is, 0.6 grams. 34 cases of Plasmodium vivax in children, the third day after taking the blood film review has been