论文部分内容阅读
57例分24小时尿白蛋白排泄量（UAE）正常组14例，微量白蛋白尿（亚临床期糖尿病肾病）组21例，临床蛋白尿22例。结果：57例中53例存在尿β2-MG和α1－MG浓度升高，占93％，其中14例UAE正常组患者尿β2-MG、α1－MG明显高于正常，对照组20例（P＜0．05～001）。表明糖尿病肾损害除肾小球病变外，还较普遍存在小管功能的损害。临床蛋白尿组尿β2-MG低于微量蛋白尿组．而β2-MG和α1－MG重吸收率与微量蛋白尿组相似。经治疗后尿电MG、a；－MG有所下降，但均未恢复正常，示糖尿病所致肾小管功能损害改善经侵，可逆性差。
There were 14 cases of normal urinary albumin excretion (UAE), 21 cases of microalbuminuria (subclinical diabetic nephropathy) and 22 cases of clinical proteinuria in 57 cases. Results: The urinary β2-MG and α1-MG concentrations were increased in 53 of 57 cases, accounting for 93%. The urinary β2-MG and α1-MG in 14 cases of UAE normal group were significantly higher than those in normal control group and 20 cases in control group <0.05 ~ 001). Show that diabetic nephropathy in addition to glomerular lesions, but also more common damage to the tubular function. Urinary β2-MG in clinical proteinuria group was lower than that in microalbuminuria group. The β2-MG and α1-MG reabsorption rate and microalbuminuria were similar. After treatment, urinary MG, a; -MG decreased, but did not return to normal, showing that the damage of renal tubular function caused by diabetes improved by invasion, poor reversibility.