原发性血小板增多症(ET)是一类造血系统慢性骨髓增生性疾病,其临床特点是外周血中血小板持续增高,同时骨髓中巨核细胞过度增生。ET的发病机制目前尚未完全明确。近来有学者发现体外诱导CD34+细胞分化得到的巨核细胞具有明显的凋亡特征,是巨核细胞成熟晚期的表 Essential thrombocythemia (ET) is a group of chronic myeloproliferative diseases of the hematopoietic system whose clinical features are the continued increase in platelets in peripheral blood and hyperproliferation of megakaryocytes in the bone marrow. The pathogenesis of ET is not yet completely clear. Recently, some scholars have found that in vitro induction of CD34 + cells differentiated megakaryocytes have obvious apoptotic features, is the late megakaryocyte maturation of the table