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丝裂霉素被认为可抑制成纤维细胞增殖,业己用于青光眼手术。作者对此作了3.5年的研究,最短随访6个月。29例患者33眼行小梁切除术。病例选自手术可能不成功者。患眼只限于新生血管性青光眼、无晶体性青光眼、继发性青光眼、进行性低眼压性青光眼和既往作过手术的眼。方法:作以角膜缘为基底的结膜瓣后,再作一约1/3～1/2巩膜厚度的2×3mm长方形巩膜瓣并延伸入透明角膜。手术当日配制0.2mg/ml丝裂霉素溶液。用一小的手术海绵浸泡该溶液后,将其紧贴于外露的巩膜表面和巩膜瓣底部,并以结膜瓣覆盖,5分钟后取下海
Mitomycin is thought to inhibit fibroblast proliferation and has been used in glaucoma surgery. The author made a 3.5-year study, the shortest follow-up of 6 months. Twenty-nine patients underwent trabeculectomy. Case selected from surgery may not be successful. The affected eye is confined to neovascular glaucoma, aphakic glaucoma, secondary glaucoma, progressive hypotony glaucoma, and previously surgically treated eyes. Methods: After the limbal conjunctival flap was made, a 2 × 3 mm rectangular scleral flap about 1/3 ~ 1/2 sclera thickness was made and extended into the transparent cornea. On the day of operation, a 0.2 mg / ml mitomycin solution was prepared. After soaking the solution with a small surgical sponge, it was brought into close contact with the exposed scleral surface and the scleral flap base and covered with a conjunctival flap. After 5 minutes the sea was removed