药物代谢和药代动力学面临的一个主要挑战应尽可能早地由体外模型数据对人体做出预测。近期在美国佛罗里达州的奥兰多召开药物代谢的体外筛选会议,报道了此领域的新进展。任何可预测性的体外系统必须发展新型的测定法、正确的体内系统模型及增加对体内生物学知识的了解。细胞色 A major challenge in drug metabolism and pharmacokinetics should be to predict the human body from in vitro model data as soon as possible. Recently, an in vitro drug screening screening meeting was held in Orlando, Florida, USA, and new progress in this area was reported. Any predictable in vitro system must develop new assays, correct in vivo system models, and increase understanding of in vivo biological knowledge. Cytochrome