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近年来我们采用雄黄治疗急性早幼粒细胞性白血病(APL)取得满意疗效,现报告如下.1 材料和方法1.1 临床资料 初治APL 9例,其中男性6例,女性3例.年龄24～52岁,平均31.6岁.临床均表现有贫血Hb 45～96 g/L,5例发热(T 38.4℃～40.2℃),6例有皮肤及/或粘膜出血BPC 28～72×10~9/L.骨髓检查早幼粒细胞占0.68～0.85,其中粗颗粒型5例,细颗粒型3例,欧氏小体型1例.Fig<1.8g/L者2例,PT延长>3s者3例,三p试验(+)者2例,但以上各例均未达到DIC诊断标准.1.2 治疗方法 将市售雄黄研末装入胶囊中,每粒1g,口眼6g/日.不同时使用维甲酸、化疗及其它治
In recent years, we have used realgar to treat acute promyelocytic leukemia (APL) with satisfactory results. The current report is as follows.1 Materials and methods 1.1 Clinical data 9 patients were initially treated with APL, including 6 males and 3 females. Years old, average 31.6 years old. The clinical manifestations were anemia Hb 45 ~ 96 g / L, 5 cases of fever (T 38.4 °C ~ 40.2 °C), 6 cases of skin and / or mucosal bleeding BPC 28 ~ 72 × 10 ~ 9 / L Promyelocytic leukemia cells accounted for 0.68 to 0.85, including 5 cases of coarse-grained type, 3 cases of fine-grained type, 1 case of Euclide small-body type, 2 cases of Fig<1.8 g/L, and 3 cases of PT prolongation of >3 s. Three p test (+) were found in 2 cases, but none of the above cases met the DIC diagnostic criteria. 1.2 Treatments were filled with realgar in commercial capsules, 1 g per capsule, 6 g/day in the mouth of eyes. , chemotherapy and other treatments