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膀胱癌是泌尿系统最常见的恶性肿瘤,术后复发率高达60％以上,采用化疗药灌注疗效不佳,卡介苗灌注可明显降低复发率,但副作用较严重、绿脓杆菌MSHA菌毛株菌苗(简称PA菌毛株菌苗)具有很强的免疫原性、基础及实验研究已证实对肿瘤有明显的治疗作用。1993年3月经过动物实验证实PA菌毛株菌苗用于预防膀胱癌术后复发的可行性,对32例膀胱癌术后病人采用PA菌毛株菌苗膀胱灌注预防其术后复发、初步观察疗效显著、没有副作用,现报告如下。
Bladder cancer is the most common malignant tumor of the urinary system. The postoperative recurrence rate is over 60%. The curative effect of chemotherapeutic drug infusion is poor. BCG infusion can significantly reduce the recurrence rate, but the side effects are more serious. Pseudomonas aeruginosa MSHA fimbriae vaccine (Referred to as PA fimbriae vaccine) has a strong immunogenicity, basic and experimental studies have confirmed that the tumor has a significant therapeutic effect. March 1993 after animal experiments confirmed the use of PA strains of hair follicles for the prevention of postoperative recurrence of bladder cancer feasibility of 32 cases of bladder cancer patients with PA strains of hair follicles after vaccination to prevent their recurrence after surgery, preliminary Observed a significant effect, no side effects, are as follows.