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绒毛组织活检,是一项引人注目的产前诊断应用技术。这一技木的应用使胚胎遗传病早期诊断和预防工作进入了一个新阶段。实行绒毛活检虽然才有十余年的历史,但已广泛应用于优生实践,结合细胞遗传学、生化遗传学和分子遗传学技术测定胎儿优劣,决定胎儿取舍,使选优生育在妊娠二个月就可以决断。但是,绒毛取材术对所生小儿有无不良影响,是人们关注而尚处于争议中的问题。因此,我们在86年5月至87年3月对10年来做过绒毛组织取材而保留妊娠的妇女随访到了271例,对其所生的274例小儿进行了系统检查,以了解绒毛组织取材术对胎(小)儿生长、发育及智力的影响。
Villus tissue biopsy is a striking prenatal diagnostic application technology. The application of this technique has brought the early diagnosis and prevention of embryo genetic diseases into a new phase. Although the implementation of villus biopsy has only ten years of history, but it has been widely used in the practice of eugenics, combined with cytogenetics, biochemical and molecular genetics technology to determine the merits of fetus, fetal decision-making, so that the optimal selection of children in pregnancy two Month can decide. However, whether the villus harvesting has an adverse effect on the infants born is a matter of concern and still in dispute. Therefore, from May to March 1987, we followed up 271 women who had had their pregnancy preserved in 10 years and had undergone villus retrieval. We conducted a systematic examination of 274 infants who had undergone them to understand villus tissue harvesting Impact on fetal growth, development and intelligence.