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目的探讨戊酸雌二醇合并红霉素软膏及高锰酸钾治疗幼儿及学龄前儿童小阴唇粘连的疗效及安全性。方法回顾分析2006年1月～2010年12月广东省惠东县妇幼保健院门诊收治的幼儿及学龄前儿童阴唇粘连共42例,给予1:5 000高锰酸钾坐浴及戊酸雌二醇粉与红霉素软膏混合涂抹外阴,观察小阴唇粘连情况,有无阴道出血,乳腺大小及外阴局部皮肤颜色变化等。结果 42例患儿经上述治疗7～12d,外阴粘连均自然分离,所有患儿外阴及大腿内侧接受浸泡部位皮肤颜色均有改变,3周后恢复正常。42例患儿均无阴道出血发生,无乳腺异常发育现象。结论高锰酸钾联合戊酸雌二醇及红霉素软膏治疗幼儿及学龄前儿童阴唇粘连安全、简便、经济、有效。
Objective To investigate the efficacy and safety of estradiol valerate combined with erythromycin ointment and potassium permanganate in the treatment of small labia of young children and preschool children. Methods A retrospective analysis of 42 cases of labial and preschool children ’s labial adhesions admitted from January 2006 to December 2010 in Huidong Maternal and Child Health Hospital of Guangdong Province was given 1: 5000 potassium permanganate bath and female valerate Alcohol powder and erythromycin ointment mixed smear vulva, observe the labia minora adhesions, with or without vaginal bleeding, breast size and vulvar local skin color changes. Results 42 cases of children treated by the above 7 ~ 12d, vulvar adhesions were isolated, all children received the soles of the vulva and inner thigh skin color change, returned to normal after 3 weeks. 42 cases of children without vaginal bleeding, no abnormal breast development. Conclusion Potassium permanganate combined with estradiol valerate and erythromycin ointment is safe, simple, economical and effective for the labial and preschool labia.