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目的 为MRI诊断颅底凹陷症提供正常参考标准。方法 对 10 0例没有中枢神经系统症状及体征的国人以及 6例颅底凹陷症患者行颅脑矢状位MRI扫描 ,于正中矢状层面上测量脑桥、延髓轴线与上颈髓轴线的夹角。结果 男女两性该角度的差别没有统计学意义 ,国人延髓、上段颈髓轴线夹角正常参考值为 143 6 4°～ 16 5 42°(95 %可信区间 ) ,颅底凹陷症患者该角度的估计范围为 12 4 84°～ 131 16°(95 %可信区间 ) ,二者间无交叉。结论 对于颅底凹陷症的诊断 ,MR能够直接显示脑桥延髓受压的情况 ,在MRI成像中可以应用参考上述正常参考值对于该疾病作出正确的诊断。
Objective To provide a normal reference standard for MRI diagnosis of skull base depression. Methods The cranial sagittal MRI scan was performed in 10 0 Chinese people without central nervous system symptoms and signs and 6 patients with skull base depression. The angle between the medulla oblongata axis and the medullary axis was measured on the median sagittal plane . Results There was no significant difference between male and female in this angle. The normal reference value of the angle between the medulla oblongata and the upper cervical spinal cord was 143 6 4 ° ~ 165 42 ° (95% confidence interval). The angle of the skull base depression The estimated range is 12 4 84 ° to 131 16 ° (95% confidence interval), with no crossover between them. Conclusion For the diagnosis of skull base depression, MR can directly show the pontine compression of the pontine. MRI imaging can be used to make the correct diagnosis of the disease by referring to the above normal reference values.