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传统的肿瘤光动力疗法是利用集聚在肿瘤中的外源光敏剂吸收激发光后启动光动力反应 ,产生活性产物扑杀肿瘤组织。氨乙酸丙酸 (ＡＬＡ)是人体生理过程中血红素合成中的基本原料 ,是原卟啉的前体。在正常组织中ＡＬＡ转变成原卟啉后 ,在亚螯合物酶的作用下 ,再与Ｆｅ+ + 结合成血
Traditional photodynamic therapy of tumors utilizes an exogenous photosensitizer that accumulates in the tumor to absorb the excitation light and then initiate the photodynamic reaction to produce active products that cull the tumor tissue. Aminoacetic acid propionic acid (ALA) is the basic raw material for heme synthesis in human physiological processes and is the precursor of protoporphyrins. After the ALA is converted into protoporphyrins in normal tissues, it is combined with Fe+ + into blood under the action of sub-chelating enzymes.