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目的 研究低分子量肝素 -速避凝对白内障术后眼内炎症反应的预防作用。方法 110例老年性白内障随机分为 2组 ,并盲法给药。在进行白内障囊外摘除及后房人工晶体植入手术中 ,对照组灌注液为乳酸钠林格氏液 ,实验组灌注液为乳酸钠林格液中加入速避凝浓度为 6U/ml。术后 1、3及 7d观察眼内纤维蛋白渗出、房水混浊及眼内出血情况。结果 实验组术后第 1、3、7d眼内纤维蛋白渗出及房水混浊轻于对照组 (P <0 .0 5 ) ,两组术中及术后出血差异无显著性 (P >0 .1)。结论 速避凝能有效抑制白内障术后眼内炎症反应 ,并且不增加眼内出血危险性。
Objective To study the preventive effect of low molecular weight heparin - fast Avoidance on intraocular inflammatory response after cataract surgery. Methods 110 cases of senile cataract were randomly divided into two groups, and blindly administered. In the extracapsular cataract extraction and posterior chamber intraocular lens implantation surgery, the control group perfusion solution of sodium lactate Ringer’s solution, the experimental group perfusion solution of sodium lactate Ringer solution was added to the concentration of 6U / ml. At 1, 3 and 7 days after operation, intraocular fibrin exudation, aqueous humor and intraocular hemorrhage were observed. Results The intraocular fibrin exudation and aqueous humor of the experimental group were lighter than those of the control group on the 1st, 3rd, 7th day after operation (P <0.05). There was no significant difference between the two groups in intraoperative and postoperative bleeding (P> 0 .1). Conclusion Avoidance of coagulation can effectively inhibit intraocular inflammation after cataract surgery, and does not increase the risk of intraocular hemorrhage.