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目的探讨阿奇霉素序贯疗法治疗老年支气管肺炎的临床疗效。方法选取2014年6—12月如皋市中医院收治的老年支气管肺炎患者139例,按治疗方法不同分为观察组(70例)与对照组(69例)。对照组患者予以头孢唑肟治疗,观察组患者予以阿奇霉素序贯疗法治疗。观察两组患者临床疗效、治疗前后临床症状评分及不良反应发生情况。结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05);治疗前两组患者咳嗽、咳痰、喘息、哮鸣音评分比较,差异无统计学意义(P>0.05),治疗后观察组患者咳嗽、咳痰、喘息、哮鸣音评分低于对照组,差异有统计学意义(P<0.05);观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论阿奇霉素序贯疗法治疗老年支气管肺炎的临床疗效显著,可改善患者的临床症状,且不良反应少。
Objective To investigate the clinical efficacy of sequential treatment of azithromycin in elderly patients with bronchopneumonia. Methods 139 elderly patients with bronchopneumonia admitted from June to December 2014 in Rugao Hospital of Traditional Chinese Medicine were divided into observation group (70 cases) and control group (69 cases) according to the different treatment methods. Patients in the control group were treated with ceftizoxime and patients in the observation group were given azithromycin sequential therapy. The clinical efficacy, clinical symptom scores and adverse reactions before and after treatment were observed in two groups of patients. Results The total effective rate in the observation group was higher than that in the control group (P <0.05). There was no significant difference in cough, expectoration, wheezing and wheeze scores between the two groups before treatment (P> 0.05 ), And the scores of cough, expectoration, wheezing and wheeze in the observation group were lower than those in the control group after treatment (P <0.05), and the incidence of adverse reactions in the observation group was lower than that of the control group Significance (P <0.05). Conclusion Sequential azithromycin treatment of bronchial pneumonia in elderly patients with significant clinical efficacy, can improve the clinical symptoms of patients with less adverse reactions.