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急性白血病(AL)的诱导缓解已取得瞩目的进展,成人AL的完全缓解(CR)率已达60%~80%,但较长时间存活的病例仍不多。为更广泛地了解AL的发展规律及预后判断,以指导治疗,现就临床观察到的一些指标,分析长生存与高危因素如下。 1 资料与方法 我院1979~1988年共收治经临床、骨髓象及组化染色而确诊的各型AL233例,对初诊时观察到的指标和治疗情况进行分析。经治疗达到缓解而存活(从确诊至死亡或统计时止)3年以上的病例为A组,共15例(含1979年以前治疗的2例),
There have been remarkable progress in the induction of acute leukemia (AL). The complete remission (CR) rate of adult AL has reached 60% to 80%, but the survival rate of AL is still low. To understand more about the development of AL and prognosis to guide the treatment, is now on the clinical observation of some of the indicators, analysis of long-term survival and risk factors are as follows. 1 Materials and Methods 1979 to 1988 in our hospital were treated by clinical, bone marrow and histochemical staining confirmed AL233 cases of various types of indicators and treatment of newly diagnosed cases were analyzed. Patients who survived for more than 3 years after their diagnosis of remission survived (from the time of diagnosis to death or statistics) were Group A with a total of 15 patients (including 2 patients treated before 1979)