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例1 女,20岁,于1989年6月2日给予腰麻,行膝关节手术。术后第二天体温达38.5℃,逐渐升至40℃,持续不退,头痛剧烈,喷射状呕吐,脑膜刺激状明显。脑脊液呈脓性,培养为绿脓杆菌。采用常规药物治疗,给多种抗菌素治疗3个月疗效不佳,配合鞘内注射多粘菌素2.5u万,每日1次,连用10天,病情稍有缓解,但因注射后双下肢剧痛,每次持续3～4小时,用冬眠全量也不能控制,被迫停用,改颈内动脉注射多粘菌素,每次50万u,每日1次,连续应用10天,使体
Example 1 Female, 20 years old, on June 2, 1989 given spinal anesthesia, knee surgery. On the second postoperative day, the body temperature reached 38.5 ℃ and gradually rose to 40 ℃. The patient suffered from severe headache, jet-like vomiting and obvious meningeal irritation. Cerebrospinal fluid was purulent, cultured Pseudomonas aeruginosa. The use of conventional drug treatment, to a variety of antibiotics 3 months curative effect is poor, with polyunsuits intrathecal 2.5u million, 1 day, once every 10 days, the condition a little relief, but after the injection of both lower extremities Pain, each lasting 3 to 4 hours, the total amount can not be controlled with the hibernation, was forced to stop, change the injection of polymyxin within the internal carotid artery, each 500 000 u, day 1, continuous application of 10 days, the body