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20世纪80年代起,由于术前评估手段的快速发展和临床的广泛应用,通过手术治疗难治性癫痫的例数显著增加。对难治性癫痫致痫灶的术前精确定位是手术能否成功的关键;近年来,同步脑电图-功能性磁共振(Simultaneous EEG-fMRI)作为一种无创的术前定位方法逐渐应用于临床,在进行功能性磁共振扫描的同时描记脑电数据,根据EEG出现癫痫波的时间点作为时间相关曲线对fMRI数据进行分析,通过测定发作间期痫样放电的血流动力学效应来定位致痫灶,可以将解剖定位与功能定位相结合,为临床医师提供一种新的、精确度较高的定位方法。
Since the 1980s, due to the rapid development of preoperative evaluation methods and the wide application of clinical practice, the number of cases of intractable epilepsy treated by surgery has been significantly increased. Precise preoperative localization of intralesional epilepsy in refractory epilepsy is the key to successful operation. In recent years, Simultaneous EEG-fMRI has been gradually applied as a non-invasive preoperative localization method In clinical practice, EEG data were recorded at the same time of functional magnetic resonance (MR) scans, and fMRI data was analyzed as a time-dependent curve based on the time point of epileptic wave in EEG. By measuring the hemodynamic effects of epileptiform discharge Locating the epileptogenic zone can combine the anatomical and functional positioning to provide the clinician with a new and accurate method of localization.