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目的探讨高血压脑出血的治疗方法。方法采用静滴20%甘露醇125ml,8h/次;重症者加用速尿,2次/d。每日加用抑肽酶278U溶于生理盐水250ml静脉滴注,连用7d。结果治愈16例,显效21例,有效5例,死亡8例,生存率84%,病死率16%。死亡8例。结论抑肽酶主要作用是抑制激肽蛋白原的激活和缓激肽的形成。常被用于治疗各种出血性疾病或减少手术出血,是否对控制颅内出血有作用,还值得进一步研究。
Objective To investigate the treatment of hypertensive cerebral hemorrhage. Methods intravenous infusion of 20% mannitol 125ml, 8h / times; severe cases plus furosemide, 2 times / d. Daily plus aprotinin 278U dissolved in saline 250ml intravenous infusion, once every 7d. Results of 16 cases were cured, markedly effective in 21 cases, effective in 5 cases, 8 cases of death, the survival rate of 84%, the mortality rate of 16%. 8 died. Conclusion The main role of aprotinin is to inhibit the activation of kininogen and the formation of bradykinin. Often used to treat various hemorrhagic diseases or reduce surgical bleeding, whether to control the role of intracranial hemorrhage, but also worthy of further study.