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本文报道巯甲丙脯氨酸(Captopril)并用速尿治疗顽固性重度高血压10例的良好疗效。10例平均年龄39岁(17～70岁),其中除3例为原发性外,余均为小动脉粥样硬化性肾血管病变或肾炎等原因引起的高血压。治疗前全组平均动脉压均>140毫米汞柱,最高血压平均达258/151毫米汞柱,其中7例曾具一次或多次血压急剧增高,曾经β-阻滞剂、哌唑嗪、肼苯达嗪、甲基多巴等治疗无效。
This article reports the good effect of captopril and furosemide in the treatment of refractory severe hypertension in 10 cases. The average age of 10 patients was 39 years old (17 to 70 years old), except for 3 cases of primary hypertension, they were all caused by atherosclerotic renal vascular disease or nephritis and other causes of hypertension. Before treatment, the mean arterial pressure of the whole group was> 140 mmHg. The highest blood pressure reached an average of 258/151 mmHg. Among them, 7 cases had one or more sudden increases in blood pressure. Once β-blockers, prazosin, Bendazine, methyl dopa and other treatment is invalid.