论文部分内容阅读
目的 探讨原发性肝癌病人的乙肝病毒活动状态和肝切除术对乙肝病毒活动状态的影响。方法 选取近期我院资料完整的３０ 例经病理证实的肝癌肝切除患者，手术前后分别检测乙肝血清标志物及ＨＢＶＤＮＡ。结果 术前、术后乙肝血清标志物总阳性率（ 总感染率） 均为１００％ ，以表现为“小三阳”（ 即ＨＢｓＡｇ、ＨＢｅＡｂ、ＨＢｃＡｂ ３项阳性） 者为主，分别占７１．３％ 和６２．５％ 。ＨＢＶＤＮＡ、ＨＢｅＡｇ 等病毒复制指标手术前后无明显差异。结论 原发性肝癌与乙型肝炎关系密切，但大多数患者为非肝炎活动期，肝癌切除手术对病毒活动状态影响较小。
Objective To investigate the status of hepatitis B virus in patients with primary liver cancer and the effect of hepatectomy on the activity of hepatitis B virus. Methods Thirty patients with hepatocellular carcinoma confirmed by pathology who had complete data in our hospital were selected. Serum markers of hepatitis B and HBV DNA were detected before and after surgery. RESULTS: The total positive rate of total serum markers of hepatitis B before and after surgery (total infection rate) was 100%, and the performance was mainly “small three positive” (ie, HBsAg, HBeAb, and HBcAb were positive), accounting for 71.3% respectively. % and 62.5%. There were no significant differences in the replication parameters of HBV DNA, HBeAg and other viruses before and after surgery. Conclusions Hepatocellular carcinoma is closely related to hepatitis B, but most patients are active in non-hepatitis. Liver cancer resection has little effect on the activity of the virus.