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目的:观察准分子激光屈光性角膜切削术(PRK)治疗近视、散光的疗效,探讨影响疗效的相关因素。方法:采用VISX20/2O型准分子激光仪对306例(529眼)近视、散光患者进行PRK手术。术前等值球镜屈光度为-1.00~16.00D(-6.55±3.19D),分为两组:Ⅰ组:-1.00~6.00D,294眼;Ⅱ组:-6.25~16.00D,235眼。随访3~12个月。结果:术后12个月,裸眼视力≥0.5、1.0者在Ⅰ组分别为97.5%、77.5%,在Ⅱ组分别为80.3%、32.8%;实际矫正度在预测矫正度±1.00D内者在Ⅰ、Ⅱ组分别为92.5%、42.6%。影响术后屈光度变化的因素:术后角度上皮下雾状混浊(Haze)程度、去上皮的方法、眼压、术前中央角膜厚度。结论:PRK治疗-6.00D以内的近视是一种安全、稳定、预测性强、有效的方法。术前应根据屈光度、年龄、角膜厚度、眼压、设计手术方案,术中强调采用激光去除上皮。眼科学报1997;13:75~78
Objective: To observe the effect of excimer laser photorefractive keratectomy (PRK) on myopia and astigmatism and to explore the related factors that affect the curative effect. Methods: 306 patients (529 eyes) with myopia and astigmatism underwent PRK surgery with VISX20 / 2O excimer laser. Preoperative spherical equivalent refraction was -1.00 ~ 16.00D (-6.55 ± 3.19D), divided into two groups: Ⅰ group: -1.00 ~ 6.00D, 294 eyes; Ⅱ group: -6.25 ~ 16.00D, 235 eyes. Follow-up 3 to 12 months. Results: At 12 months after operation, uncorrected visual acuity ≥0.5 and 1.0 were 97.5% and 77.5% respectively in group Ⅰ and 80.3% and 32.8% respectively in group Ⅱ, and those in actual group were Group Ⅰ and Ⅱ were 92.5% and 42.6% respectively. Factors affecting postoperative refractive power: the degree of subcutaneous haze after surgery, the method of de-epithelialization, intraocular pressure, preoperative central corneal thickness. Conclusion: PRK treatment of myopia within -6.00D is a safe, stable, predictive and effective method. Preoperative should be based on diopter, age, corneal thickness, intraocular pressure, the design of surgical options, intraoperative emphasis on the use of laser to remove the epithelium. Journal of Ophthalmology 1997; 13: 75 ~ 78