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急性有机磷农药中毒(AOPP)是常见的急危重症之一,为提高临床救治率,多种新型治疗方法在临床得到认可。本研究就AOPP的中毒机制,经典药物胆碱酯酶复活药、抗胆碱能药的应用近况,其他类药物的新型应用如脂肪乳及血液净化治疗、中西医联合疗法作一综述,全面阐述这些药物及治疗方法在临床中的应用及取得的疗效。“,”Acute organophosphorus pesticide poisoning (AOPP) is one of the common critical diseases.In order to improve the rate of clinical cure, in recent years, many new treatment methods in clinical are recognized.In this paper, we will make a overview from the mechanism of AOPP, the application of classical drug cholinesterase reactivators, anticholinergicdrugs, other new applications such as fat emulsion for AOPP and blood purification therapy, combination therapy of Chinese and Western medicine, comprehensively elaborate the application of these drugs and treatment methods in clinical and therapeutic effect.