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羊水中板层小体(LB)富含卵磷脂,是肺表面活化物质合成与储存的场所。LB由肺泡Ⅱ型细胞排出后可附于胎肺泡腔表面,并随肺液流入羊水中,随着胎肺成熟,羊水中LB数量增多,据此可估计胎肺成熟度、预测呼吸窘迫综合征(RDS)发生率。该法在预测胎肺成熟度方面优于传统磷酯分析并有较高的阴性预测值。LB计数快速、省力、简单、廉价、客观,在有电子细胞计数仪的实验室均能开展,有很高的临床应用价值。
Amniotic fluid lamellar body (LB) is rich in lecithin, lung surfactant synthesis and storage of places. LB is excreted by alveolar type II cells can be attached to fetal alveolar surface, and with pulmonary fluid into the amniotic fluid, as fetal lung maturity, amniotic fluid in the increase in the number of LB, which can be estimated based on fetal lung maturity, prediction of respiratory distress syndrome (RDS) incidence. This method is superior to conventional phosphate ester analysis in predicting fetal lung maturity and has a high negative predictive value. LB count fast, labor-saving, simple, cheap, objective, electronic cytometry in the laboratory can be carried out, a high clinical value.