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血吸虫童虫对过氧化氢介导的杀伤作用较敏感。本文报道感染曼氏血吸虫小鼠的腹腔巨噬细胞,无论经过特异性或非特异性刺激,均能降低过氧化氢的杀虫作用。作者用CD-1雌性小鼠采集腹腔渗出细胞(PEC),其中有的鼠未感染,有的感染曼氏血吸虫达8～10周,或在采集前5及4天分别腹腔注射BCG或3％Brewer’s巯基乙酸酯(THGL),所得的腹腔渗出细胞分别为U-PEC、S-PEC、BCG-PEC和FHGL-PEC。S-PEC含10～20％嗜酸粒细胞,BCG-PEC含20～
Schistosomula Schistosoma is more sensitive to hydrogen peroxide-mediated killing. In this paper, we report that peritoneal macrophages infected with Schistosoma mansoni can reduce the insecticidal effect of hydrogen peroxide, whether through specific or nonspecific stimulation. The authors collected peritoneal exudate cells (PECs) from CD-1 female mice, some of which were uninfected, others were infected with Schistosoma mansoni for 8 to 10 weeks, or BCG or 3, respectively, intraperitoneally 5 and 4 days prior to collection % Brewer’s Thioglycollate (THGL). The resulting peritoneal exudate cells were U-PEC, S-PEC, BCG-PEC and FHGL-PEC, respectively. S-PEC contains 10 to 20% of eosinophils, BCG-PEC containing 20 ~