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目的观察丙泊酚不同配伍在无痛人流中的镇痛效果和安全性。方法将300例要求行无痛人工流产的患者随机分为试验组(K组,丙泊酚联合利多卡因,n=150)及对照组(F组,丙泊酚联合芬太尼,n=150),观察注射部位疼痛、呼吸、循环变化和麻醉恢复时间等。结果两组有效率为100%,无1例发生人流综合症。观察项目中F组注射部位疼痛、呼吸抑制发生率较高,定向力恢复时间较长,与K组比较p<0.05,有统计学差异。结论丙泊酚联合利多卡因静脉麻醉用于无痛人流,安全有效,减少了副作用。
Objective To observe the analgesic effect and safety of different compatibility of propofol in painless abortion. Methods 300 patients with painless induced abortion were randomly divided into test group (group K, propofol combined with lidocaine, n = 150) and control group (group F, propofol combined with fentanyl, n = 150), observe the injection site pain, respiration, circulation changes and anesthesia recovery time. Results The two groups had an effective rate of 100%, and no one had abortion syndrome. In the observation group, pain in the injection site of Group F, higher incidence of respiratory depression and longer recovery time of directional force were observed in group F, with p <0.05 compared with that in group K, showing statistical difference. Conclusion Propofol combined lidocaine intravenous anesthesia for painless, safe and effective, reducing the side effects.